Entecavir In-house Spec.

Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection.

 

Entecavir is a nucleoside analog (more specifically, a guanosine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir).

 

Entecavir was originally approved by the U.S.FDA in March 2005.

 

USES Entecavir is used to treat chronic hepatitis B. It also helps prevent the hepatitis B virus from multiplying and infecting new liver cells. Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection. However, entecavir is not active against HIV.

 

Its dosage forms and strengths are SOLUTION and TABLET;  0.05MG/ML,0.5MG,1MG.

 

General Data:

CAS No.:

142217-69-4, 209216-23-9 (monohydrate)

Molecular Formula:

C12H15N5O3·H2O

Molecular Weight:

295.30

Appearance:

white to almost white powder

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