Terlipressin In-house Spec.

Active substance
Terlipressin is a synthetic analogue of vasopressin used as a vasoactive drug in the management of hypotension. It is a prodrug, which is converted to (Lys8)- vasopressin after removal of the N-terminal triglycine in vivo. Terlipressin has a longer duration of action and a better safety profile than the parent compound.

CAS No.

14636-12-5

Molecular Formula

C52H74N16O15S

Molecular Weight
1227.37

Sequence

H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: 4-9)

Fields of application

Norepinephrine-resistant septic shock

Hepatorenal syndrome

Acute variceal hemorrhage (esophageal varices)

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